By contrast co-stimulation of HVEM via BTLA and CD160 did not influence the proliferation of CD4 + and CD8 + T cells and although HVEM stimulation via LIGHT slightly increased the proliferation of CD4 + and CD8 + T cells this trend did not reach statistical significance ( Figures 6B, C ; Supplementary Figure 6A ).
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BTLA inhibition has a dominant role in the <i>cis</i>-complex of BTLA and HVEM.
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