The addition of ALA showed a trend of improvement in psychopathology, neurotrophic factors, and oxidative stress parameters.
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Effect of add-on alpha lipoic acid on psychopathology in patients with treatment-resistant schizophrenia: a pilot randomized double-blind placebo-controlled trial.
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The sentences
There was an increasing trend in serum BDNF but add-on placebo had better effect when compared with ALA, though change in neither of the groups was significant individually.