Hispanic ethnicity and the rs4880 variant in SOD2 are associated with elevated liver enzymes and bilirubin levels in children receiving asparaginase-containing chemotherapy for acute lymphoblastic leukemia.

Biomed Pharmacother · 2022 · PMC9450009 · PMID 35658244

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did not reach statistical significanceno p-value reported

While the frequency of hepatotoxicity among the CC genotype was higher than that among the CT and TT genotypes, the association between the SOD2 rs4880 genotypes and hepatotoxicity did not reach statistical significance in univariate or multivariate analysis.

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