A significant impairment of insulin tolerance was observed in HFD mice when compared to ND mice, however, insulin sensitivity showed a trend toward improvement in HFD iNAC+ mice compared to HFD mice, but statistical significance was not reached ( Figures 5I, J ) .
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N-acetyl-L-cysteine treatment reduces beta-cell oxidative stress and pancreatic stellate cell activity in a high fat diet-induced diabetic mouse model.
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