Interleukin 4 Controls the Pro-Tumoral Role of Macrophages in Mammary Cancer Pulmonary Metastasis in Mice.

Although there was a trend towards a reduced foci number, foci size and metastatic index in heterozygous mice ( IL4Rα + / − ) compared to WT mice, this reduction did not reach statistical significance when comparing WT and IL4Rα + / − mice or IL4Rα + / − and IL4Rα − / − mice ( Figure 2 (Bi,Bii,Biii)).

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