Association between Serum Level of Multiple Trace Elements and Esophageal Squamous Cell Carcinoma Risk: A Case-Control Study in China.

Cancers (Basel) · 2022 · PMC9455051 · PMID 36077776

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a positive trendno p-value reported

Notably, the dose–response relationship between ESCC risk and serum V, Ni and Sr concentration was an inverted U-shape, whereas serum Al concentration showed a positive trend with ESCC.

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a negative trendno p-value reported

Three elements (Zn, Se and Sr) displayed a negative trend with risk for ESCC, and a significant overall effect of the mixture of Al, V, Mn, Ni, Zn, Se and Sr on ESCC was found, with the effects of V, Ni and Sr being nonlinear.

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