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Functional Intercellular Transmission of miHTT via Extracellular Vesicles: An In Vitro Proof-of-Mechanism Study.

Cells · 2022 · PMC9455173 · PMID 36078156

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Interestingly, the percentage of shorter miHTT isomiRs was higher in EV-enriched fractions (isolated from donor miHTT overexpressing cell conditioned media) than in donor or recipient (HEK-293T or HeLa) cells, although it did not reach statistical significance.

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