Assessment of the Proton Pump Inhibitor, Esomeprazole Magnesium Hydrate and Trihydrate, on Pathophysiological Markers of Preeclampsia in Preclinical Human Models of Disease.

Int J Mol Sci · 2022 · PMC9455231 · PMID 36076929

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a clear trendno p-value reported

Consistently in this study, esomeprazole MH reduced secretion of sFLT-1 by primary cytotrophoblast and HUVECs, whereas at a matched concentration, esomeprazole MTH only reduced sFLT-1 secretion in cytotrophoblast; however, there was a clear trend for reduction in the HUVECs.

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