Association between squamous cell carcinoma antigen level and EGFR mutation status in Chinese lung adenocarcinoma patients.

If using tripartite SCCAg grouping [96 cases in Tertile 1 (0.29–0.67), 89 cases in Tertile 2 (0.68–0.99), and 108 cases in Tertile 3 (1.00–11.50)], the relationship between different levels of SCCAg and EGFR mutation probability showed a trend of first flattening and then decreasing [70.8% (68/96), 68.5% (61/89), and 45.4% (49/108), p < 0.001]; after fully adjusted for covariates, the probability of EGFR mutation was 70.8% (95% CI: 52.9%–84.0%), 74.5% (95% CI: 56.6%–86.8%) and 55.1% (95% CI: 35.4%–73.2%) with the increase of SCCAg level

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