There were numerically more patients with “Other” histology in the group with total tumor volume greater than 65 mL, but this did not reach statistical significance (8/58, 14% vs. 2/52, 4%; P=0.10).
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Tumor volume as a predictor of cell free DNA mutation detection in advanced non-small cell lung cancer.
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Multivariate analysis showed that age, mutation detection and presence of bone metastases were independently associated with OS, but there was also a trend toward significance for total tumor volume greater than 65 mL and presence of liver metastases.