Synthesis and Activity of 2-Acyl-cyclohexane-1,3-dione Congeners Derived from <i>Peperomia</i> Natural Products against the Plant p-Hydroxyphenylpyruvate Dioxygenase Herbicidal Molecular Target Site.

Plants (Basel) · 2022 · PMC9459959 · PMID 36079655

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showed a trendno p-value reported

This class, along with cyclohexane-1,3-diones with phenyl side chains, phenylene side chains, or other side chains additionally showed a trend in which the addition of a R2 methyl group had a more positive binding energy and a less-efficient IC50 value, possibly due to stearic hindrance.

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