Epithelial immunomodulation by aerosolized Toll-like receptor agonists prevents allergic inflammation in airway mucosa in mice.

Assessing changes in the systemic immune response, Pam2ODN treatment reduced serum immunoglobulin E (IgE) levels by >50% ( Figure 4G ), including a strong trend towards reducing OVA-specific IgE levels ( Figure 4H ), but total IgG ( Figure 4I ) and IgG1 ( Figure 4J ) were unchanged.

also in 5,725 other papers