nominally significantP = 0.004
In contrast, genes near TET2 -associated sites showed nominally significant depletion for HSC marker genes (OR = 0.46; P = 0.004), though were enriched for marker genesets for naïve T cells, monocytes, and neutrophils (1 × 10 −14 < P < 0.0008; Supplementary Fig. 9 ).