Barely Significant
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Itaconic acid facilitates inflammation abatement and alleviates liver ischemia-reperfusion injury by inhibiting NF-κB/NLRP3/caspase-1 inflammasome axis.

Ann Transl Med · 2022 · PMC9469154 · PMID 36111043

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showed a trendno p-value reported
The expression of NLRP3, GSDMD, caspase-1, and IL-1β showed a trend from feeble to intense but weakened at 120 min of reoxygenation.

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