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Genetic and chemical validation of <i>Plasmodium falciparum</i> aminopeptidase <i>Pf</i>A-M17 as a drug target in the hemoglobin digestion pathway.

Elife · 2022 · PMC9470162 · PMID 36097817

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Between all groups, there was no statistical difference after the addition of GlcN, and while there appeared to be an upward trend in the free heme in GlcN treated Pf A-M17-HAglmS parasites compared to untreated, this did not reach statistical significance ( Figure 7D ).

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