Although inverse associations were found for all subgroups, most did not reach statistical significance (Tables 5 , 6 ).
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Energy balance-related factors and risk of colorectal cancer based on KRAS, PIK3CA, and BRAF mutations and MMR status.
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However, a borderline significant inverse association was found between non-occupational physical activity and risk of the any-mutation/dMMR subgroup [HR 30min/day (95% CI): 0.97 (0.92–1.02), p -trend categories : 0.050], whereas no association was found for the all-wild-type + pMMR subgroup.