Barely Significant
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Reduced white matter venous density on MRI is associated with neurodegeneration and cognitive impairment in the elderly.

Front Aging Neurosci · 2022 · PMC9475309 · PMID 36118685

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a positive trendno p-value reported
Although there is no significant correlation, we observed that there is a positive trend of WM venous density to CDR sum of boxes score, indicating the potential alteration of oxygenation level with different degrees of cognitive and functional impairment.

also in 11,005 other papers

a negative trendno p-value reported
Further analysis of clinical features revealed a negative trend of WM venous density with the sum-of-boxes of Clinical Dementia Rating and a significant association with category fluency (1-min animal naming).

also in 4,201 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.