Although there is no significant correlation, we observed that there is a positive trend of WM venous density to CDR sum of boxes score, indicating the potential alteration of oxygenation level with different degrees of cognitive and functional impairment.
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Reduced white matter venous density on MRI is associated with neurodegeneration and cognitive impairment in the elderly.
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The sentences
Further analysis of clinical features revealed a negative trend of WM venous density with the sum-of-boxes of Clinical Dementia Rating and a significant association with category fluency (1-min animal naming).