Recent advances and limitations of mTOR inhibitors in the treatment of cancer.

Cancer Cell Int · 2022 · PMC9476305 · PMID 36109789

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quite significantno p-value reported

Because Akt is involved in numerous pro-survival and growth-promoting pathways, the continuous stimulation of Akt by mTORC2 with the combination of sirolimus in the setting of cancer is quite significant.

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