ELISpot analysis revealed significantly lower numbers of IFN-γ SFU in HSCT recipients compared with HC and a slightly significant positive correlation between the ELISpot and the TCR-seq results ( Figure 1 D, upper panel).
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T cell receptor sequencing reveals reduced clonal breadth of T-cell responses against SARS-CoV-2 after natural infection and vaccination in allogeneic hematopoietic stem cell transplant recipients.
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