Sirtuin 6 inhibition protects against glucocorticoid-induced skeletal muscle atrophy by regulating IGF/PI3K/AKT signaling.

Nat Commun · 2022 · PMC9478160 · PMID 36109503

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However, Dex-treated control mice showed a trend toward decrease in soluble protein concentration, although the changes were not statistically significant (Supplementary Fig. 12K ).

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