Barely Significant
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Vascular Closure Devices versus Manual Compression in Cardiac Interventional Procedures: Systematic Review and Meta-Analysis.

Cardiovasc Ther · 2022 · PMC9482152 · PMID 36134143

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did not reach statistical significancep = 0.05actually significant
Similar to the result of total complications, bleeding-related complication rates were found to be lower with use of VCD compared with MC in cardiac interventional procedures, but did not reach statistical significance (RR: 0.77, random-effect model, 95% CI, 0.60 to 1.00, p = 0.05; Figure 5(c) ).

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