The effect of smoking on survival in lung carcinoma patients with brain metastasis: a systematic review and meta-analysis.

Neurosurg Rev · 2022 · PMC9492581 · PMID 35831518

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did not reach statistical significanceno p-value reported

Progression-free survival The pooled multivariate HR for PFS demonstrated worse outcomes amongst smokers (HR: 1.35, 95% CI 0.68, 2.68; 5 studies; I 2 : 80.8%; p-heterogeneity: 0.0003), when compared to non-smokers; however, this analysis did not reach statistical significance (supplementary materials Fig. 4 ) (Fig. 4 ).

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