The Genetic Architecture of Non-Syndromic Rhegmatogenous Retinal Detachment.

Genes (Basel) · 2022 · PMC9498391 · PMID 36140841

Europe PMC DOI

hedged sentence

0.0800

closest p · 1.6× alpha

0.0800

boldest claim

The sentences

failed to reach statistical significancep = 0.08so close (0.05 < p ≤ 0.1)

The CC homozygous genotype was also associated with an increased odds of 1.9, but failed to reach statistical significance ( p = 0.08); this variant has been shown to impact the role of p53 to induce apoptosis and is a recognised risk factor for malignancy [ 34 , 35 ].

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