Exosomes Derived from Human Umbilical Cord Mesenchymal Stem Cells Accelerate Diabetic Wound Healing via Promoting M2 Macrophage Polarization, Angiogenesis, and Collagen Deposition.

Int J Mol Sci · 2022 · PMC9498995 · PMID 36142334

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In contrast to the previous findings stimulated by at least 100 μg of exosomes, our results, induced by only 10 μg of exosomes per wound, showed a trend of the relative increase in the expression of CD31 and VEGF at the middle and late stages, resulting in enhanced angiogenesis in H&E-stained tissues.

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