The MicroRNA-106a/20b Strongly Enhances the Antitumour Immune Responses of Dendritic Cells Pulsed with Glioma Stem Cells by Targeting STAT3.

As shown in Figure 8(b) , the cytotoxicities against GSCs at E/T ratios of 10 : 1, 20 : 1, and 30 : 1 in the miR-106a/20b mimic-transfected DC/T cell coculture groups were higher than those in the mimic control group (∗ p < 0.05), but the T cells showed a trend towards lower cytotoxicity at each of the different E/T ratios in the miR-106a/20b inhibitor-transfected groups compared with the inhibitor control groups, although this difference was not statistically significant (∗ p < 0.05)).

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