A causal variant rs3769823 in 2q33.1 involved in apoptosis pathway leading to a decreased risk of non-small cell lung cancer.

Cancer Biol Med · 2022 · PMC9500222 · PMID 36047776

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did not reach statistical significanceno p-value reported

Although the difference did not reach statistical significance, caspase-8K14R also showed a higher apoptosis rate than caspase-8WT after treatment with 0 ng/mL or lower concentrations of TRAIL ( Figure 5C ).

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