Comparing Current and Next-Generation Humanized Mouse Models for Advancing HIV and HIV/<i>Mtb</i> Co-Infection Studies.

Both models had more than 10% of human CD4+ T cells expressing the HIV-associated co-receptor CCR5, and there was a clear trend towards a higher absolute number of human CD4+ T cells expressing CCR5 in the blood of huDRAG-A2 mice compared to huNRG mice at 20 weeks post-engraftment ( Figure 1 E,F). 3.2. huDRAG-A2 and huNRG Mice Infected with HIV Demonstrate Hallmark Characteristics of Infection Well-engrafted (%hCD45 of tota

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