did not reach statistical significancep = 0.0794
CSE Increased in Human Brain Endothelial Cells, AMPs, and BMPs in Response to TNF-α/IFN-γ Treatment We observed that exposure of human brain endothelial cells to TNF-α/IFN-γ for 72 h significantly increased the overall cellular expression of the sulfide-producing enzyme CSE ( p = 0.0147) by approximately 50%, and increased the release of CSE + AMPs by nearly threefold ( p = 0.0181), while the release of CSE + BMPs was approximately doubled, although this did not reach statistical significance ( p = 0.0794). 3.2.