The Effect of Dietary Carbohydrate and Fat Manipulation on the Metabolome and Markers of Glucose and Insulin Metabolism: A Randomised Parallel Trial.

Nutrients · 2022 · PMC9505524 · PMID 36145067

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0.0510

closest p · 1.0× alpha

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boldest claim

The sentences

showed a trendp = 0.051so close (0.05 < p ≤ 0.1)

FGF21 showed a trend ( p = 0.051) in overall change in participants following the LCHF diet after decreasing from a median (IQR) of 148.16 (203.49) to 99.4 (92.43) pg/mL at week 4 and increasing again to 167.38 (152.08) pg/mL at week 8, with post-hoc analysis reporting a trend ( p = 0.069) between baseline and week 4, whereas no change was observed in HCLF.

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a decreasing trendp = 0.053so close (0.05 < p ≤ 0.1)

Post-hoc analysis reported LAR levels to be significantly lower at week 4 ( p = 0.049) and week 8 ( p = 0.004) compared with baseline in the LCHF group; however, in the HCLF group only week 4 showed a decreasing trend ( p = 0.053) compared to baseline.

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