Influence of DNA-Polymorphisms in Selected Circadian Clock Genes on Clock Gene Expression in Subjects from the General Population and Their Association with Sleep Duration.

Medicina (Kaunas) · 2022 · PMC9506325 · PMID 36143969

Europe PMC DOI

hedged sentences

0.0670

closest p · 1.3× alpha

0.0670

boldest claim

The sentences

did not reach statistical significancep = 0.067so close (0.05 < p ≤ 0.1)

However, in this last lifestyle factor, we detected a lower VRK2 expression in smokers, but it did not reach statistical significance (β: −1.30 ± 0.70; p = 0.067), Table S1 . 3.3.

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highly significantno p-value reported

A polygenic risk score (PRS) for each clock gene was created by the unweighted sum of the highly significant clock SNP related with circadian phenotypes.

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