Vitamin D Supplementation Does Not Influence SARS-CoV-2 Vaccine Efficacy or Immunogenicity: Sub-Studies Nested within the CORONAVIT Randomised Controlled Trial.

Nutrients · 2022 · PMC9506404 · PMID 36145196

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Exploratory Responder Analysis An exploratory responder analysis, restricted to participants randomised to either intervention arm for whom end-trial 25(OH)D levels were available, showed a trend towards higher end-trial anti-S IgGAM titres in participants who did vs. did not attain end-trial 25(OH)D concentrations ≥75 nmol/L (adjusted percentage difference 17.6%, 95% CI -0.3% to 38.8%).

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