Barely Significant
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Glucosamine Use Is Associated with a Higher Risk of Cardiovascular Diseases in Patients with Osteoarthritis: Results from a Large Study in 685,778 Subjects.

Nutrients · 2022 · PMC9506459 · PMID 36145069

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a significant trendno p-value reported
Among 774,912 patients newly diagnosed with osteoarthritis whether or not they took glucosamine within one year, the glucosamine use was significantly associated with CVD, CHD, and stroke with a significant trend for each ( p for trend < 0.001) ( Table S9 ).

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