Association between germ-line HLA and immune-related adverse events.

Front Immunol · 2022 · PMC9513190 · PMID 36177028

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nominally significantno p-value reported

We first tested the association between HLA types and irAEs of different organs in our ICI treatment cohort (nominally significant HLA variants shown in Figure 4 ), then validated this association by comparing the frequency of HLA types between participants with irAEs and the Novegene cancer reference cohort and the healthy MHC-Han Chinese reference cohort.

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