Barely Significant
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Irisin stimulates protective signaling pathways in rat hippocampal neurons.

Front Cell Neurosci · 2022 · PMC9518673 · PMID 36187295

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0.0700
closest p · 1.4× alpha
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boldest claim

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showed a trendp = 0.07so close (0.05 < p ≤ 0.1)
FNDC5 z-scores also showed a trend of inverse association with pThr181-tau immunoreactivity in the hippocampus (Pearson r = −0.30; p = 0.07) ( Figure 2G ).

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