Testing for association with rare variants in the coding and non-coding genome: RAVA-FIRST, a new approach based on CADD deleteriousness score.

PLoS Genet · 2022 · PMC9518893 · PMID 36112662

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hedged sentence

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closest p · 0.0× alpha

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boldest claim

The sentences

reached borderline significancep = 6.41∙10 −7actually significant

One association reached borderline significance (p = 6.41∙10 −7 ) when using the RAVA-FIRST strategy, i.e. with CADD regions and the corresponding ACS filtering.

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