Tyk2 is a tumor suppressor in colorectal cancer.

Oncoimmunology · 2022 · PMC9519006 · PMID 36185806

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showed a trendno p-value reported

Additional FACS analysis for PD-1 + T cell populations showed a trend of CD8 + T cell exhaustion in Tyk2 Δ/Δ and Tyk2 ΔIEC tumors, but this was not significant (Supplementary Figure 5c, o, p).

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