Therapeutic Properties of Highly Selective β-blockers With or Without Additional Vasodilator Properties: Focus on Bisoprolol and Nebivolol in Patients With Cardiovascular Disease.

Cardiovasc Drugs Ther · 2022 · PMC9519665 · PMID 34106365

Europe PMC DOI

hedged sentence

0.0600

closest p · 1.2× alpha

0.0600

boldest claim

The sentences

a strong trendp = 0.06so close (0.05 < p ≤ 0.1)

However, there was a strong trend (p = 0.06) towards a larger decrease in heart rate 3 h after administration with bisoprolol (mean change –24 bpm) vs. nebivolol (mean change –15 bpm) in the randomised NEBIS study [ 58 ].

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