Epigenomic profiling of glucocorticoid responses identifies cis-regulatory disruptions impacting steroid resistance in childhood acute lymphoblastic leukemia.

Leukemia · 2022 · PMC9522591 · PMID 36028659

Europe PMC DOI

hedged sentence

0.0770

closest p · 1.5× alpha

0.0770

boldest claim

The sentences

a strong trendp = 0.077so close (0.05 < p ≤ 0.1)

Importantly, GREs were significantly more enriched at GC-specific active STARR-seq sites in 697 cells compared to 0 h-specific active STARR-seq sites (Chi-square p = 1.3 × 10 −4 , 1.5-fold) and exhibited a strong trend for greater enrichment in Nalm6 cells (Chi-square p = 0.077, 1.6-fold).

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