Pre-existing humoral immunity and complement pathway contribute to immunogenicity of adeno-associated virus (AAV) vector in human blood.

Front Immunol · 2022 · PMC9523746 · PMID 36189251

Europe PMC DOI

hedged sentence

—

closest p

—

boldest claim

The sentences

did not reach statistical significanceno p-value reported

There was also a trend towards lower AAV uptake in APL-9-treated moDCs and monocytes from NAb-negative donors, although it did not reach statistical significance ( Figure 8A ).

also in 111,027 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.