Canakinumab for the treatment of autoinflammatory very early onset- inflammatory bowel disease.

At six months there was an overall improvement in nutritional status, with resolution of malnutrition in all patients and the median weight for length Z score increased from -1.01 (-2.34-0.9) to 1.1 (0.05-1.99, p<0.01) and BMI Z score increases from 0.08 (-2.37-0.92) to 0.68 (-0.89-3.27), although it did not reach statistical significance ( Table 3 ).

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