Immunological risk factors for sepsis-associated delirium and mortality in ICU patients.

Among the sepsis patients, the association between delirium and the risk for mortality was weakly significant (nondelirium vs. delirium: 9.1% vs. 47.1%, p = .049) ( Table 1 ).

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Multiple linear regression analysis showed that the high expression of IL-6 and TNF-α and low levels of C3 significantly increased the likelihood of mortality in the ICU, whereas other variables failed to achieve significance in multivariate testing ( Figure 3E , Table S9 ).

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