nearly significantp = 0.053
There was a nearly significant main effect of genotype on HOMA-IR (F 1, 26 = 4.12, p = 0.053; Figure 7F ) with increased HOMA-IR in WT females relative to KO, and as expected increased HOMA-IR in HFD females relative to LFD (F 1, 26 = 8.83, p = 0.0063).