Immune defects associated with lower SARS-CoV-2 BNT162b2 mRNA vaccine response in aged people.

JCI Insight · 2022 · PMC9536264 · PMID 35943812

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Three weeks after the vaccination with the first dose, young participants < 60 years old showed a trend to decrease the percentages of naive T cells and to increase memory T cells and showed the restoration of T cell subset distribution that occurred 2 months after the second dose ( Figure 3C ).

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