Lifestyle Affects Amyloid Burden and Cognition Differently in Men and Women.

Ann Neurol · 2022 · PMC9542817 · PMID 35598071

Europe PMC DOI

hedged sentences

0.0090

closest p · 0.2× alpha

0.0750

boldest claim

The sentences

highly significantp = 0.009actually significant

This became particularly evident when we compared men and women in this cognitively healthy subsample: there was a highly significant association between MVR and cognition in men (β = −0.300, SE = 0.115, p = 0.009) whereas the association was not significant in women (β = −0.037, SE = 0.105, p = 0.723).

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approached significancep = 0.075so close (0.05 < p ≤ 0.1)

Both groups showed similar associations between amyloid and cognition, which approached significance in men ( p = 0.075) and women ( p = 0.079).

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a trend toward significanceno p-value reported

Here, the MVR‐to‐amyloid path showed a trend toward significance in women and reached significance after excluding participants with MCI.

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