Bone Microenvironment-Suppressed T Cells Increase Osteoclast Formation and Osteolytic Bone Metastases in Mice.

J Bone Miner Res · 2022 · PMC9543062 · PMID 35635377

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hedged sentences

0.0540

closest p · 1.1× alpha

0.0649

boldest claim

The sentences

almost significantp = 0.0540so close (0.05 < p ≤ 0.1)

Similarly, there was an almost significant increase of CD69 + T cells (13.95% ± 3.53% versus 4.50% ± 0.92%, p = 0.0540) (Fig. 5 D ).

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not quite statistically significantp = 0.0648so close (0.05 < p ≤ 0.1)

Histomorphometric analysis indicated that the tumor area was increased (×1.38) in normal mice compared to T‐cell depleted, although close to but not quite statistically significant ( p = 0.0648) (Fig. 3 B ).

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did not reach statistical significancep = 0.0649so close (0.05 < p ≤ 0.1)

In 4T1 bone metastases, the amount of CD62L − T cells in the bone marrow increased within the T cell population (23.5% ± 3.71% versus 31.38% ± 8.28% of T cells) compared to cancer‐free mice although it did not reach statistical significance ( p = 0.0649) (Fig. 5 C ).

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