It is particularly noteworthy that the RRR for the composite renal endpoint increased considerably (to a 40% reduction in risk) and became nominally significant when a threshold change of a ≥50% decrease in eGFR and renal death were included in the analysis and when the analysis was confined to patients with ejection fraction <60%.
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Outcomes with empagliflozin in heart failure with preserved ejection fraction using DELIVER-like endpoint definitions.
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