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Characterization of transit rates in the large intestine of mice following treatment with a CGRP antibody, CGRP receptor antibody, and small molecule CGRP receptor antagonists.

Headache · 2022 · PMC9545683 · PMID 35822594

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Female mice receiving 0.03 and 0.3 mg/kg of atogepant showed a reduction in the proportion of large intestine containing charcoal meal relative to the vehicle‐treated mice that did not reach statistical significance (Figure 5A ).

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