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Proteolytically generated soluble Tweak Receptor Fn14 is a blood biomarker for γ-secretase activity.

EMBO Mol Med · 2022 · PMC9549706 · PMID 36069059

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showed a trendno p-value reported
In the patient groups with an initial GBM diagnosis (iGBM) or with a recurrent GBM (rGBM), the sFn14 concentration was in a similar range but showed a trend to an increase in the rGBM group.

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