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Hemp seed significantly modulates the endocannabinoidome and produces beneficial metabolic effects with improved intestinal barrier function and decreased inflammation in mice under a high-fat, high-sucrose diet as compared with linseed.

Front Immunol · 2022 · PMC9552265 · PMID 36238310

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showed a trendno p-value reported
Thus, it appears that hemp seed substitution mitigated the HFHS-induced increase in PAI-1 levels, even though it only showed a trend toward a decrease as compared to the HFHS group.

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