While Communication (mean delta −7.5 points) and Cognitive Impairment (mean delta −5.0 points) domains of PDQ-39 also had clinically meaningful improvements from baseline to week 24 in the overall cohort, they did not reach statistical significance; in addition, these changes were not accompanied by statistically significant improvements in voice-related quality of life, as consistent with Shih et al.
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Parkinsonics: A Randomized, Blinded, Cross-Over Trial of Group Singing for Motor and Nonmotor Symptoms in Idiopathic Parkinson Disease.
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